We offer bi-annual progress report and seminar rounds which are related to the ExCarBon research topics. Researchers who are involved in ExCarBon projects will have the opportunity to present their data.

Seminars 2024

Date Presenter Title
18.01.2024 Jian Mei (Ortho) Caspases-1/-8 and chondrocyte: drug target effect and osteoarthritis pathology
Gopala Mannala (UCh) Bacteriophage loaded 3D printed alginate gels to reduce implant-associated infections
08.02.2024 Nicole Schäfer (Ortho) The role of α-MSH on senescent human osteoarthritic chondrocytes
Sophia Rohrmüller (MKG) PD-L1 trafficking in head and neck cancer cells
15.02.2024 Alissa Behn (Ortho) Adipose-derived stem cell therapy for the treatment of pain in osteoarthritis: effects of filtered human lipoaspirates in an in vitro OA model
Raphaëlle Youf (UCh) Development of antimicrobial strategies against biofilm-related infections in trauma surgery
29.02.2024 Annika Walter (Krankenhaushygiene) Analysis of Staphylococcus aureus facultative intracellular survival
11.04.2024 Dietmar Zaiss (UKR, Immune Cell Communication) Linkage between local inflammation and TGF-beta activity as an orchestrator of tissue homeostasis
16.05.2024 Patrick Pann (Ortho) ExCarBon Subproject 4 - Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology
Maximilian Zirkel (UCh)  
23.05.2024 Raphaëlle Youf (UCh) Development of antimicrobial strategies against biofilm-related infections in trauma surgery
Panis Duymaz (MKG)  
06.06.2024 You Zhao (UCh) The effect of antibiotic-loaded bone cement (ALBC) on multidrug-resistant Gram-positive bacteria in the Galleria mellonella implant infection model
Jian Mei (Ortho) Caspases-1/-8 and chondrocyte: drug target effect and osteoarthritis pathology
20.06.2023 Markus Böhm (Hautklinik Münster) Is the alpha-MSH-MC1R axis relevant for cutaneous photoaging?
27.06.2023 Nicole Schäfer (Ortho) The role of alpha-MSH on senescent human osteoarthritic chondrocytes
     

Seminars 2023

Date Presenter Title
19.01.2023 Nicole Schäfer (Ortho) The role of alpha-MSH on senescent human osteoarthritic chondrocytes
Daniela Schulz (MKG) Differential cell cycle dependent nuclear PD-L1 variants of head and neck cancer cells
23.02.2023 Gopala-K. Mannala (UCH) Bacteriophages delivery using 3d hydrogel and poly electrolyte coating approaches against implant associated infections
Chenglong Wang (Ortho) Human osteogenic differentiated BMSCs derived EVs rescue osteogenic ability of hBMSCs impaired by hypoxia
09.03.2023 Guest: Rafal Poreba
(IMC Prague)
Surface modification preventing protein, cell and bacteria attachment to biomaterials
20.04.2023 Guest: Prof. Markus Böhm
(Uniklinik Münster)
A role for α-MSH in skin aging?
01.06.2023 Girish Pattappa (UCH)  Meniscus Functionalised Scaffold To prevent kneeOosteoarthritis onset after meniscectomy (MEFISTO)
Dominique Rubenich (MKG) Characterization of the Crosstalk between HNSCC and Neutrophils via Adenosine-producing Tumor-derived Exosomes
15.06.2023 PD Jürgen Fritsch (UKR) Regulation of TNF-R1 mediated signal transduction pathways
- ADAM15: a new player?
22.06.2023 Patrick Pann (Ortho) ExCarBon SP4 - Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology
You Zhao (UCH) Evaluation of the antimicrobial effect of antibiotic-loaded PMMA-bone cement (ALBC)
06.07.2023 Nicole Schäfer (Ortho) The role of α-MSH on senescent human osteoarthritic chondrocytes
13.07.2023 Daniela Schulz (MKG) Nuclear PD-L1 variants in head and neck cancer cells
Sophia Rohrmüller (MKG) PD-L1 trafficking in head and neck cancer cells
27.07.2023 Hannah Köck (Ortho) Complement C5a Inhibitor AON-D21 – A New Therapeutic Approch for Osteoarthritis?
Jian Mei (Ortho) Caspase-1 and chondrocytes: role in cellular senescence and osteoarthritis pathology
03.08.2023 Gopala Mannala (UCH) Repetitive Combined Doses of Bacteriophages and Gentamycin Protect Against Staphylococcus Aureus Implant-Related Infections in Galleria Mellonella
Raphaëlle Youf (UCH) Alternatives to Antibiotherapies Against Multidrug Resistant Pathogens: Applications for Respiratory and Implant-Related Infections
19.10.2023 Girish Pattappa (UCh) Meniscus Functionalised Scaffold To prevent kneeOosteoarthritis onset after meniscectomy (MEFISTO)
Hendrik Roetzheim (UCh) Quantification of serum soluble RANKL and OPG and the correlation to bone turnover in Spondylodiscitis patients
02.11.2023 Stephanie Seebauer (Ortho) Improvement of mechanical properties of osteoarthritic cartilage by infiltrating zwitterionic hydrogel
Dominique Rubenich (MKG) Characterization of the Crosstalk between HNSCC and Neutrophils via Adenosine-producing Tumor-derived Exosomes
09.11.2023 Patrick Pann (Ortho) ExCarBon Subproject 4 - Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology
You Zhao (UCh) Evaluation of the antimicrobial effect of antibiotic-loaded PMMA-bone cement (ALBC)
30.11.2023 Hannah Köck (Ortho) Complement C5a Inhibitor AON-D21 - A New Therapeutic Approach for Osteoarthritis
Daniel Froschhammer (MKG) Influence of the interaction of mesenchymal stem cells with head and neck tumor cells on osteoinvasion

Contact

Prof. Dr. rer. nat. Susanne Grässel

University Hospital Regensburg

Orthopedic Surgery, Div. Experimental Orthopedics

Biopark I - ZMB

Am Biopark 9

D-93053 Regensburg

 

Tel.: +49 (0) 941 943 5065

Fax: +49 (0) 941 943 5066

E-mail: susanne.graessel@ukr.de