We offer bi-annual progress report and seminar rounds which are related to the ExCarBon research topics. Researchers who are involved in ExCarBon projects will have the opportunity to present their data.
Seminars 2025
| Date | Presenter | Title |
|---|---|---|
| 08.05.2025 | Markus Böhm (Hautklinik Münster) | alpha-MSH and skin aging – concepts results and future perspectives |
| 15.05.2025 | Zhiheng Kong (Ortho) | Effect of Osteoarthritic Chondrocyte-Derived Extracellular vesicles on Synovial Inflammation and Fibrosis |
| 05.06.2025 | Tabea Klaes (MKG) | PD-L1-Integrin Crosstalk in head and neck tumor cell migration |
| 26.06.2025 | Luc Brasz (UCh) | Proof of concept of light-based therapies against orthopedic infections |
| STSM students (Uch guests) | Short Term Scientific Mission - STSM | |
| 02.07.2025 | Toby Jenkins (University of Bath) | New methods and developing models for studying and controlling skin and wound infection |
| 10.07.2025 | Patrick Pann (UCh) | Quality of Minced Human Articular Cartilage From Focal Early Osteoarthritic Defects for Regenerative Cartilage Repair |
| Gopala Mannala (UCh) | BACTERIOPHAGE LOADED 3D PRINTED ALGINATE GELS TO REDUCE IMPLANT-ASSOCIATED INFECTIONS | |
| 24.07.2025 | Bára Křižovská (University of Praque) | Plant-derived molecules targeting bacterial resistance mechanisms |
| Filip Vilotic (Krankenhaushygiene) | Staphylococcus aureus survival in host cells: The interplay of intracellular trafficking cell death and the influence of SSL10 on TNFa-linked signalling | |
| 06.11.2025 | Nicole Schäfer (Ortho) | The alpha-MSH – MC1R axis on senescence and inflammation processes in human articular chondrocytes and mice knee joints |
| Jian Mei (Ortho) | Genetic and multiomics evidence reveal Caspase-8 as a causal regulator of human chondrocyte signaling and phenotypic networks in osteoarthritis | |
| 13.11.2025 | Renata Padilha Guedes (University Porto Alegre) | Neuroprotective Strategies in Diet-Induced Obesity: Insights from Preclinical Models |
| Elizandra Braganhol (University Porto Alegre) | Purinergic signaling as innovative target for immunotherapy | |
| 04.12.2025 | Fabian Schürz and Lucas Lehner (Uch) | The combined use of antimicrobial peptides and antibiotics in the fight against implant-related infections |
| 11.12.2025 | Dr Ewa Kijenska (Cezamat, Warschau) | Introduction to Cezamat, HyFiDress Project and Electrospinning Technology |
| Dr Jurr van Ramshorst (Bioprex, Amsterdam) | Bioprex - Novel antimicrobial coatings for biomedical devices |
Seminars 2024
| Date | Presenter | Title |
|---|---|---|
| 18.01.2024 | Jian Mei (Ortho) | Caspases-1/-8 and chondrocyte: drug target effect and osteoarthritis pathology |
| Gopala Mannala (UCh) | Bacteriophage loaded 3D printed alginate gels to reduce implant-associated infections | |
| 08.02.2024 | Nicole Schäfer (Ortho) | The role of α-MSH on senescent human osteoarthritic chondrocytes |
| Sophia Rohrmüller (MKG) | PD-L1 trafficking in head and neck cancer cells | |
| 15.02.2024 | Alissa Behn (Ortho) | Adipose-derived stem cell therapy for the treatment of pain in osteoarthritis: effects of filtered human lipoaspirates in an in vitro OA model |
| Raphaëlle Youf (UCh) | Development of antimicrobial strategies against biofilm-related infections in trauma surgery | |
| 29.02.2024 | Annika Walter (Krankenhaushygiene) | Analysis of Staphylococcus aureus facultative intracellular survival |
| 11.04.2024 | Dietmar Zaiss (UKR, Immune Cell Communication) | Linkage between local inflammation and TGF-beta activity as an orchestrator of tissue homeostasis |
| 16.05.2024 | Patrick Pann (Ortho) | ExCarBon Subproject 4 - Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology |
| Maximilian Zirkel (UCh) | ||
| 23.05.2024 | Raphaëlle Youf (UCh) | Development of antimicrobial strategies against biofilm-related infections in trauma surgery |
| Panis Duymaz (MKG) | ||
| 06.06.2024 | You Zhao (UCh) | The effect of antibiotic-loaded bone cement (ALBC) on multidrug-resistant Gram-positive bacteria in the Galleria mellonella implant infection model |
| Jian Mei (Ortho) | Caspases-1/-8 and chondrocyte: drug target effect and osteoarthritis pathology | |
| 20.06.2023 | Markus Böhm (Hautklinik Münster) | Is the alpha-MSH-MC1R axis relevant for cutaneous photoaging? |
| 27.06.2023 | Nicole Schäfer (Ortho) | The role of alpha-MSH on senescent human osteoarthritic chondrocytes |
| 18.07.2024 | Annika Walter (Krankenhaushygiene) | Analysis of Staphylococcus Aureus Facultative Intracellular Survival |
| Sophia Rohrmüller (MKG) | PD-L1 trafficking in head and neck cancer cells | |
| 25.07.2024 | Shushan Li (Ortho) | Extracellular vesicles derived from the lesioned cartilage promote the osteoarthritis process |
| Gopala Mannala (UCh) | Bacteriophage Loaded 3D Printed Alginate Gels to Reduce Implant-Associated Infections | |
| 01.08.2024 |
Amelie Biberger & Jana Krieger |
The combined use of antimicrobial peptides and antibiotics in the fight against implant-related infections |
| 17.10.2024 | You Zhao (UCh) | Antibiotic-loaded PMMA bone cement is effective in Galleria mellonella model mimicking periprosthetic joint infection with cemented implants |
| Shushan Li (Ortho) | Extracellular vesicles derived from the lesioned cartilage promote the osteoarthritis process | |
| 31.10.2024 | Zhiheng Kong (Ortho) | Effect of Osteoarthritic Chondrocyte-Derived Extracellular Vesicles on Synovial Inflammation and Fibrosis |
| 14.11.2025 | Martijn Riool (UCh) | |
| 28.11.2024 | Group of Jürgen Fritsch (Krankenhaushygiene) | |
| Nicole Schäfer (Ortho) | The role of alpha-MSH on senescent human osteoarthritic chondrocytes | |
| 05.12.2024 | Luc Brasz (UCh) | Proof of concept of light-based therapies against orthopedic infections |
| Patrick Pann (Ortho) | ExCarBon Subproject 4 - Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology | |
| 12.12.2024 | Gopala Mannala (UCh) | BACTERIOPHAGE LOADED 3D PRINTED ALGINATE GELS TO REDUCE IMPLANT-ASSOCIATED INFECTIONS |
| Sophia Rohrmüller (MKG) | PD-L1 trafficking in head and neck cancer cells |
Seminars 2023
| Date | Presenter | Title |
|---|---|---|
| 19.01.2023 | Nicole Schäfer (Ortho) | The role of alpha-MSH on senescent human osteoarthritic chondrocytes |
| Daniela Schulz (MKG) | Differential cell cycle dependent nuclear PD-L1 variants of head and neck cancer cells | |
| 23.02.2023 | Gopala-K. Mannala (UCH) | Bacteriophages delivery using 3d hydrogel and poly electrolyte coating approaches against implant associated infections |
| Chenglong Wang (Ortho) | Human osteogenic differentiated BMSCs derived EVs rescue osteogenic ability of hBMSCs impaired by hypoxia | |
| 09.03.2023 |
Guest: Rafal Poreba (IMC Prague) |
Surface modification preventing protein, cell and bacteria attachment to biomaterials |
| 20.04.2023 |
Guest: Prof. Markus Böhm (Uniklinik Münster) |
A role for α-MSH in skin aging? |
| 01.06.2023 | Girish Pattappa (UCH) | Meniscus Functionalised Scaffold To prevent kneeOosteoarthritis onset after meniscectomy (MEFISTO) |
| Dominique Rubenich (MKG) | Characterization of the Crosstalk between HNSCC and Neutrophils via Adenosine-producing Tumor-derived Exosomes | |
| 15.06.2023 | PD Jürgen Fritsch (UKR) |
Regulation of TNF-R1 mediated signal transduction pathways - ADAM15: a new player? |
| 22.06.2023 | Patrick Pann (Ortho) | ExCarBon SP4 - Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology |
| You Zhao (UCH) | Evaluation of the antimicrobial effect of antibiotic-loaded PMMA-bone cement (ALBC) | |
| 06.07.2023 | Nicole Schäfer (Ortho) | The role of α-MSH on senescent human osteoarthritic chondrocytes |
| 13.07.2023 | Daniela Schulz (MKG) | Nuclear PD-L1 variants in head and neck cancer cells |
| Sophia Rohrmüller (MKG) | PD-L1 trafficking in head and neck cancer cells | |
| 27.07.2023 | Hannah Köck (Ortho) | Complement C5a Inhibitor AON-D21 – A New Therapeutic Approch for Osteoarthritis? |
| Jian Mei (Ortho) | Caspase-1 and chondrocytes: role in cellular senescence and osteoarthritis pathology | |
| 03.08.2023 | Gopala Mannala (UCH) | Repetitive Combined Doses of Bacteriophages and Gentamycin Protect Against Staphylococcus Aureus Implant-Related Infections in Galleria Mellonella |
| Raphaëlle Youf (UCH) | Alternatives to Antibiotherapies Against Multidrug Resistant Pathogens: Applications for Respiratory and Implant-Related Infections | |
| 19.10.2023 | Girish Pattappa (UCh) | Meniscus Functionalised Scaffold To prevent kneeOosteoarthritis onset after meniscectomy (MEFISTO) |
| Hendrik Roetzheim (UCh) | Quantification of serum soluble RANKL and OPG and the correlation to bone turnover in Spondylodiscitis patients | |
| 02.11.2023 | Stephanie Seebauer (Ortho) | Improvement of mechanical properties of osteoarthritic cartilage by infiltrating zwitterionic hydrogel |
| Dominique Rubenich (MKG) | Characterization of the Crosstalk between HNSCC and Neutrophils via Adenosine-producing Tumor-derived Exosomes | |
| 09.11.2023 | Patrick Pann (Ortho) | ExCarBon Subproject 4 - Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology |
| You Zhao (UCh) | Evaluation of the antimicrobial effect of antibiotic-loaded PMMA-bone cement (ALBC) | |
| 30.11.2023 | Hannah Köck (Ortho) | Complement C5a Inhibitor AON-D21 - A New Therapeutic Approach for Osteoarthritis |
| Daniel Froschhammer (MKG) | Influence of the interaction of mesenchymal stem cells with head and neck tumor cells on osteoinvasion |