We offer bi-annual progress report and seminar rounds which are related to the ExCarBon research topics. Researchers who are involved in ExCarBon projects will have the opportunity to present their data.

Seminars 2023

Date Presenter Title
19.01.2023 Nicole Schäfer (Ortho) The role of alpha-MSH on senescent human osteoarthritic chondrocytes
Daniela Schulz (MKG) Differential cell cycle dependent nuclear PD-L1 variants of head and neck cancer cells
23.02.2023 Gopala-K. Mannala (UCH) Bacteriophages delivery using 3d hydrogel and poly electrolyte coating approaches against implant associated infections
Chenglong Wang (Ortho) Human osteogenic differentiated BMSCs derived EVs rescue osteogenic ability of hBMSCs impaired by hypoxia
09.03.2023 Guest: Rafal Poreba
(IMC Prague)
Surface modification preventing protein, cell and bacteria attachment to biomaterials
20.04.2023 Guest: Prof. Markus Böhm
(Uniklinik Münster)
A role for α-MSH in skin aging?
01.06.2023 Girish Pattappa (UCH)  
Dominique Rubenich (MKG) Characterization of the Crosstalk between HNSCC and Neutrophils via Adenosine-producing Tumor-derived Exosomes
15.06.2023 PD Jürgen Fritsch (UKR) Regulation of TNF-R1 mediated signal transduction pathways
- ADAM15: a new player?
22.06.2023 Patrick Pann (Ortho) ExCarBon SP4 - Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology
You Zhao (UCH) Evaluation of the antimicrobial effect of antibiotic-loaded PMMA-bone cement (ALBC)
06.07.2023 Nicole Schäfer (Ortho) The role of α-MSH on senescent human osteoarthritic chondrocytes
13.07.2023 Daniela Schulz (MKG) Nuclear PD-L1 variants in head and neck cancer cells
Sophia Rohrmüller (MKG) PD-L1 trafficking in head and neck cancer cells
27.07.2023 Hannah Köck (Ortho) Complement C5a Inhibitor AON-D21 – A New Therapeutic Approch for Osteoarthritis?
Jian Mei (Ortho) Caspase-1 and chondrocytes: role in cellular senescence and osteoarthritis pathology
03.08.2023 Gopala Mannala (UCH) Repetitive Combined Doses of Bacteriophages and Gentamycin Protect Against Staphylococcus Aureus Implant-Related Infections in Galleria Mellonella
Raphaëlle Youf (UCH) Alternatives to Antibiotherapies Against Multidrug Resistant Pathogens: Applications for Respiratory and Implant-Related Infections

Seminars 2022

Date Presenter Title
17.03.2022 Patrick Pann (Ortho) ExCarBon Subproject 4: Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology
Marie Steulmann (UCH) The attenuation of hypertrophy in chondrogenically differentiating hMSCs via treatment with FGF18 and BMS
23.03.2022 Prof. Brian Johnstone
(OHSU Portland)
 
21.04.2022 Nicole Schäfer (Ortho) The role of α-MSH on senescent human osteoarthritic chondrocytes

Zsuzsa Jenei-Lanzl

(KGU Frankfurt)

Autonomic influences on osteoarthritis pathogenesis and progression
12.05.2022 Hannah Köck (Ortho) In vitro Analysis of Hydrogels Infiltrated Cartilage and in Hydrogels Encapsulated Chondrocytes
Girish Pattappa (UCH)  MEFISTO: Functionalisation of meniscus scaffolds to meniscus repair
25.05.2022 Sabine Stöckl (Ortho) Intraarticular injection of SP or alphaCGRP-expressing mesenchymal stem cells in DMM-induced OA mice
Gopala Mannala (UCH) Galleria mellonella as model to study fungal mediated implant bone infections
09.06.2022 Chenglong Wang (Ortho) Human osteogenic differentiated BMSCs derived EVs rescue osteogenic ability of hBMSCs impaired by hypoxia
Daniela Schulz (MKG) Differential cell cycle dependent nuclear PD-L1 variants of head and neck cancer cells
23.06.2022 Kilian Rambacher (UCH)  
Isabella Hiermer (Ortho) Determination and characterization of MC1R mutations in osteoarthritic patients
Theresia Stich (UCH) MATEGRA: advanced functionalized biomaterials for improved osteointegration of implants
12.10.2022  PD Jürgen Fritsch (UKR) Regulation of the compartmentalization of TNF-R1 mediated signal transduction by post translational modifications
20.10.2022 Pia Maierhofer (Ortho) Role of the NK1-receptor isoforms in substance P mediated regulation of osteocytic function in vitro
Theresia Stich (UCH) Enhancing in vitro osteogenesis of cells via nano-micro structuring and functionalization of Ti surfaces
03.11.2022 Edagül Bellikli (Ortho) Filtered Lipoaspirates and Osteoarthritis
Johanna Gennrich (UCH) The In-vitro cytotoxicity of NSAIDs on human meniscus cells under physiological oxygen pressure
17.11.2022 Patrick Pann (Ortho) ExCarBon SP4: Role of the Sensory Nervous System in Subchondral Bone Remodeling and Synovial Inflammation in Osteoarthritis Pathology
Girish Pattappa (UCH)  MEFISTO: Functionalisation of meniscus scaffolds to meniscus repair
08.12.2022 Dominique Rubenich (MKG) Neutrophils in cancer progression
Nils Ludwig (MKG) Characterization of pro-angiogenic functions of TGF-ß+ exosomes from head and neck squamous cell carcinoma cells
15.12.2022 Hannah Köck (Ortho) In vitro Analysis of Hydrogels Infiltrated Cartilage and in Hydrogels Encapsulated Chondrocytes
Lisa-Marie Schmid (MKG) Complement factor genes in head and neck cancer in vitro and in ovo

Contact

Prof. Dr. rer. nat. Susanne Grässel

University Hospital Regensburg

Orthopedic Surgery, Div. Experimental Orthopedics

Biopark I - ZMB

Am Biopark 9

D-93053 Regensburg

 

Tel.: +49 (0) 941 943 5065

Fax: +49 (0) 941 943 5066

E-mail: susanne.graessel@ukr.de